Even if protecting players is the intent, it usually just takes me out of the immersive RPG experience.
I want to explore a location, fight enemies, talk to NPCs etc. - but then I pick up some loot and suddenly I'm incumbered (DnD-style games) or have to play Tetris (Diabolo, Path of Exile, Titan Quest, etc.) to fit my new loot in.
It breaks my immersion to suddenly switch from resolving epic conflict XYZ to comparing stats between swords because I cannot carry both. It feels like a chore.
On Venus?